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Πλοήγηση ανά Θέμα "Organ Specificity"

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    • Aldehyde dehydrogenase 1B1: Molecular cloning and characterization of a novel mitochondrial acetaldehyde-metabolizing enzyme 

      Stagos, D.; Chen, Y.; Brocker, C.; Donald, E.; Jackson, B. C.; Orlicky, D. J.; Thompson, D. C.; Vasiliou, V. (2010)
      Ethanol-induced damage is largely attributed to its toxic metabolite, acetaldehyde. Clearance of acetaldehyde is achieved by its oxidation, primarily catalyzed by the mitochondrial class II aldehyde dehydrogenase (ALDH2). ...

    • IL-33/ST2 axis in organ fibrosis 

      Kotsiou O.S., Gourgoulianis K.I., Zarogiannis S.G. (2018)
      Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of tumorigenicity 2 receptor (ST2). IL-33/ST2 axis has long been known to play a pivotal role in immunity and cell homeostasis by ...